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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be85918513252add226ce386167019327e825dc584f5567e56bb815fab4de41a' 
  AND token = 'DgRt/s7rip1AyAhFhBDcldDGimkwApCbdp67h2Zkhvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}