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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a67d9648f3367daf9a5cd07e9aa902652913100731c745ebd557b928ae8814c' 
  AND token = 'SfuCHiOk6bkDRVWZ1BN2kh7PM8ZqUz6ThM4oeYG9xDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}