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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4285c58467c27682a73b1dbecb8dd64d46fac0d1d45cf83388244f7dbdd049' 
  AND token = 'eh+b7FpoPasQwWIPMc5G9ZazTWVmOJuDA/LOzGexGi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}