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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9546af125d9c6d53edd11719188d8c1fa9beff157a4238c130d8329f75d6d4dc' 
  AND token = 'gY2vjnjPPJenO/ED1r5apX9jrMkyhgiPie21icn3UF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}