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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451dc2a3106a02579210257eb9689e9d4ffd3c2bfc332aa88e0d9e23f55a9937' 
  AND token = '/Lpvh8+xx/SDl9deyKhCjctRn6nH4AIUBS6AxC0/seM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}