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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d5542a96c34e1045abf8eecdfbb1469bbe72b58336ab582af87f18cebfc02d' 
  AND token = 'vbRb+rhInOfTNkPFv3qzGyiW3JLdXizWupUIT2t0MTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}