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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1901f6ca778b76697cbf1b548e7794ff03795adc434e95fac1cc247822fd83b0' 
  AND token = 'UP4nZJmrXuOmg1oDBdi1isGsVFHraci1+qY3RN6tiOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}