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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e28168d61437dc27aa513a1ad6b963296fcdd8e752dfddd1e9620afc83e892b' 
  AND token = 'AgiM28Smxdu3EYGL55tZtMKjpXLdWcgt2tGE/x8UG68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}