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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e3685ae9c24e3b7859f28afadcfb97fef57a9851ec642ddead0aa6889d1df1b' 
  AND token = 'DVBGNTyUJVY4BoGja3AOr4xB/2Sot6mmoxixvxb0nAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}