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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acc3596482cb088c29c16ea5eb3956a6aa85284828869c24d5e0280a499033a' 
  AND token = 'u1XHCfLutyPHzu+aMm5rF0oSW8byk6k/u2hjoUMPIxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}