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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c918b60c99e60160ce2a022a30e24e897cac258c9f82b247a5f835027962a73' 
  AND token = 'GOFTVNrNmfBmM804G74sMHlgakgd+3d81DllYhNAF1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}