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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5178f2e1df61f54803af5c065d4c8d3116eb88a23c66596c014bf1f243fe71cf' 
  AND token = 'QnqWYGDA585eYW0soilP/MVxy+uqsrBhNcl2kSBQIhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}