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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4321c66bd455d4262049af3df85b53e18b65d86c859c5c82d8e1e527867bfa' 
  AND token = 'eF+4WBXG9ZBAEHkYEf7HpeRFeN+HCL5AkxrWjKy1DGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}