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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c44adc9c6119ec8217e160fd61e8b662005f68c13e59e37db94de6ec9b0cdd8' 
  AND token = 'ULb/1JXCsgsZLBC2xNaDoYFwZp98e/A5kTjjRkVx8vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}