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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb1125603cab6d04d1b693f8e52e751bec589a44f9c6214ff224efc0e802e03' 
  AND token = 'VQowMOF73zmu0EpKKy/ZrfpBndkLcNQeSPoSIIviuKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}