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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c7f7b7ad08bd96ff9177af8b7e54748889afe3d402cdb6d7382e94677f38d87' 
  AND token = 'I3Vcz1cWrCM5Uu0o4fiuYKkX+qB+XYzch3EyRJiYATE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}