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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7c1b75a7e868a10abbc81eff50f16d0a4e2df6a9ac5514509281d684455bb6' 
  AND token = 'Q2mL+Yey5MRrEwMFaA7wql9BJp/aOl3ZEIkZGarxdTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}