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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '673c53f7baaefe49c263016f0ec52e12d4583eb179e7b69282c766a62459791e' 
  AND token = 'lAyS8TgmMl0+ntJUwX0VweM0cr7wE7aRZD0drtpIQBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}