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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563636f30321516b8c0ec546122b7f4db726e0287610f52b9f52e73b295ae825' 
  AND token = 'xI/UR7t1fwoyQ10TgHHNAe9a4vtka21H3aA1qkU1FnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}