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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e143e6b58aa6a4af5f583dadff091fb5d891e68661cdfb6ef95224f266e73626' 
  AND token = 'j7STY5A3XNp0EtRA6bySDfmstbi7G82Lem8xSMIfIsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}