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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4adee5e33abf02c9aad3bedef886e625fa89fab47af1e61f6189efc740215d74' 
  AND token = 'wIiOAamP1sYNsX2iu7ozuag1+tXGKmVhF0/6Mm/JM2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}