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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4b4e508bff9d49be13544b735ee608f28692d6d2b4e5d5c807c58c5256f9fcf' 
  AND token = 'K1niWzCD4pMyXk+EYKpq+qNFJRR61ZKD7c2JZSRwwt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}