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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a572512832c9c2a73c810cd0333ec9f0781d4e8427d46493c59999615c6cc1e' 
  AND token = 'psSI5k2UjTIN4FCCKdoJaHsb2nOL8u4B0rpA3xZlnF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}