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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd91f455e7375f4e4eefa65dae6219aaabd5094a964c3b34db095a86147ee944c' 
  AND token = 'ghg5OVD4dw3r+otHd8KTOGtcmk4I2POSTzI01sLR1Js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}