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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8240e5b5bc1605a40eef04c568327abb127dbde73ae5669f0bf16bf13ec9f5' 
  AND token = 'YZyH5cmkOMBY7fsaQQ5eN4XOBjOShfh/8Qr7tFEWdqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}