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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25cf40f0c296cd0da16661e8e6ef4678ae74380e2a4182dcae86b0117fed68c7' 
  AND token = 'Mhl3T24OouKW8TZlezUM3/t8Wm8alRUunrjdWTb8LUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}