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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f92d9190056403eb027f32a5860daccacf71fdb4c7d7a1b26d7084cc453dbc' 
  AND token = 'f1VRqGsWG2WgGR+x/ATtpUqNtX7f5FaRhl5HKwEFNgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}