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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b7bbfd3b328f08b434d7a132b85b0eb65aa071164d6e99f4163a038c05f005' 
  AND token = 'D1Vkb9h7ceWMDxhO/lVSMCSJ/JAnAubAqu6WiXzmWuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}