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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5bd7b446487c070dfda810e3b6e5724d09256845825044ed676cd54e9f0d19f' 
  AND token = '0YMyYSo3r6Sg/DjmduiRJIipvjX9/y3F6X6fh/W0nTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}