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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e167b234bc88d33ca4e9a1a49fa3031f3e1cf9db2d85a224a6ee8f254784bc2d' 
  AND token = 'mCL+WTbLXdgPtzft4a0skODtOATHv4c6KMzm9UHhk3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}