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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd19e8dab963040060cc2d2abd66aa7e5ce0a3650b49316629cb128c72599bbb2' 
  AND token = 'C3EkPd6hKfJiHtSzV/wHOBA1csSUdAwvhmhP4+A1sGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}