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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f458368fe4fce7a15356d20739001128eb08011b8a7c5b0b4798c680789a0dbf' 
  AND token = 's9dpMM1lui9/1VBLvMGpNVmLAoIq3zR7ox0WnL1UvDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}