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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10bf239b3e9dfc7a247a8eb6b01f2cf3688c9b6f6af35bf3292b35b585001b35' 
  AND token = 'KcLQVjHCD+BCCnaomIhLPrViey7H+YW5f65EHo/ZVVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}