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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11682a9b3d5ef3f282d0bc37c87b83e70462dce2b2e4c1d5f52ee5cbe9ff9a0f' 
  AND token = 'RF6N+cNrV5iToS09DBs1GkRClimySjaLMRKtGB6bU/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}