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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fed75100b2286fc58aecb012522e44444bc88c289467eee9d90cdf6a9d0a4a9' 
  AND token = 'wVwVUqbi44mCg7GqR2Ku4klj95oQbPqwj6iGjbYU70g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}