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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72258587ac4743d1bd2fa7f8f21f421827e86678094c7cf587c829f03f52686a' 
  AND token = 'vVMrHE9yctapgK0jHRAb+8MAwWMVePfomwIn5oJxwIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}