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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e019ba27a68e6ba3f3235152d8e1a386f7719a7a2a0dca1814076369feb0581' 
  AND token = '+znMHHKCfJXa0wO9Uo/3EB9eHZp8VINiPW0PgMngc5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}