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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f22eba407dddd73b924eb6a6e6a6b2e1978486af47b45b397582d11ac8673d' 
  AND token = 'LzEXPXVqLX0j2snhJR3AmmgnxC6tF40Atx6aJh2H8AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}