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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29cd37d2269c0cef17580344d79b2e297db3beb0d22690bf4a3cd0fbf660d0e' 
  AND token = 'xpyjhBoHN87ViGkh+DrciQMEUyU1c2DMIeljJ7xS/b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}