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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3351aee34d391c24b81faae3a38cb9ebc620db6bf8b012fdec5697e7ae29028' 
  AND token = 'Zwla2Px44oHOeT0x7/2s3rOweVqnMYPZEMHjTmHc/Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}