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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a48bc6a94609d827ca9d86bdb3312fdc19da28e0f252973e13701262fd3888c' 
  AND token = 'ZTh2oZfPB24/WqD6FLWiiO+0dIe6B91sOZa4LIwT9ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}