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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a22fcf069808c07c35572a8f071063fcaef9f3e710578d25eb497a29be0c1cd' 
  AND token = 'fHPmFrDBdAP0CiNt7WNXrD1ERN9KzKoiL8OG3f8UBkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}