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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0005b314b737ab5628a44a7b4abc20221f435f8d7979d35a441b9056a65bcae7' 
  AND token = 'DxqrH1zW71w5IRhhWClyKG0iWsqiOriEeCuh1ZT7z3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}