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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e80044dcd67ba3d0322f01925ffdd2d7d2fb0c4b95fc9c45a5b8cf8e2f2d070' 
  AND token = 'L0LawR5qlwpL8oQVrG/LpEOZsH2oDfRdg2fhGS5IcrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}