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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee3aae82c7f682f83898ab1f59f0027a98f906fc4eefa66b240eba519c3ea228' 
  AND token = 'U1RVfAnhVa8uMvPgqEZfC+MVtSFlP5MXR7Xxlp4eVsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}