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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654571b65578cd9dd6ced31dc69aa9fd05b4f719b39fee90c9989740ccd84b81' 
  AND token = 'LVT5P7/X+0LNcO4f6SeSiVxSHsfZWuPqY1UVtzOMy1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}