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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d735adc4123404338f602d4b1daf13c0c0f277ac5433fa4983a84bb776a959' 
  AND token = 'xuQfBSle1Hiy3KDbrTiW+wjUDThrbdJ5FqGQnwkbAHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}