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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72184aac15cb3001b80a9339687fe3f0160da1bad14f5ed6ef109ab7ecb752dd' 
  AND token = 'txhYFPjE629X3KSU5sIAcbgiXNi+PXlo+Ov7zVd1sEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}