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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb176be30225b2dda10c44e26043afc3cdcd9003e18a0410bc543882731ed0c2' 
  AND token = 'SWWMxU3qE8e+jnTNlTZt1xLipQu3S5h5DtGX/OnYROs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}