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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecbc3d61428e8b4b1d7ae37306356aaf8feabd29f8023c7e439771133ed918ff' 
  AND token = 'fPd8/NtzZkxfO829AYLO5cHWoZDJSFR3eaDZQ4gQFNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}